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Managing the four-prong threat of CDI, antibiotics, the flu season and COVID-19 | Jodie Y. Lee, MS, MBA and David M. Lyerly, Ph.D. → Antibiotic use increases during winter months because of the diagnosis or threat of secondary bacterial pneumonias following primary viral respiratory infections. Viral respiratory infections weaken the host’s immune and innate responses, allowing bacterial pathogens, such as Streptococcus pneumoniae and Staphylococcus aureus, to infect and inflame the lung alveoli. Physicians may implement antibiotic therapy after diagnosing bacterial pneumonia, but also often use antibiotics empirically as a preemptive strike when they suspect bacterial pneumonia.

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